Technological projects portfolio


Biocontrol solution for the preventive and/or curative control of downy mildew on grapevines for use in organic agriculture

Investment: €680k

Scope: Agriculture and Environment

Scientific field(s): Biology and medicinal chemistry

Institution(s): CEA - CNRS

Development: Start-up in progress/completed

#Biocontrol #Fungicide #Winegrowing


Fungicide is essential for wine growers to combat downy mildew, which can result in a substantial loss of yield. However, conventional phytosanitary products are criticised for their harmful effects on health and the environment (appearance of resistance in pathogens, accumulation in the soil and water etc.).

The Ecophyto 2018 plan aims to reduce the use of phytosanitary products by 50% by 2025. Biocontrol, i.e. the use of substances or agents that use natural mechanisms to combat pathogens, is the main lever for achieving this ambitious aim.


Hydrogen peroxide is well-known for its antifungal effectiveness, stimulating natural defences. However, its instability in the environment makes it unusable on the scale of a cultivated parcel.

The DIONYSOS Project aims to develop a product based on stabilised hydrogen peroxide using substances naturally present in the environment.

Its impact is therefore greatly reduced compared with conventional fungicides or copper, which is widely used but the accumulation of which in soils is problematic. The effectiveness of this new solution is equivalent to those currently available on the market.


The DIONYSOS aims to develop a biocontrol solution for preventive and/or curative control of downy mildew usable in organic farming.

However, hydrogen peroxide has a broad spectrum of effects, and this solution can be extended to other indications for specialised crops (other wine growing pathogens, market gardening etc.) or even to other industrial processes based on the effect of hydrogen peroxide.