Technological projects portfolio

EMBRYOLIVE

Embryonic development monitoring device

Investment: €365k

Scope: Healthcare

Scientific field(s): Physics-Chemistry and Optics

Institution(s): Université de Versailles Saint-Quentin-en-Yvelines - CHU de Bordeaux - CHI de Poissy/St-Germain-en-Laye

Development: Transfer to industrial partner in progress / complete: I2S - Institut de Biotechnologies Jacques Boy

#InVitroFertilization #MedicalDevice #OpticalImaging

USE CASES

Infertility affects 15% of couples. IVF (in vitro fertilization) is a medically assisted reproduction solution subject to ever increasing demand.

The selection of embryos to be transferred during IVF is crucial to ensure successful implantation.

Selection is based on the morphological and kinetics criteria of the embryos (morphokinetic selection), which are assessed through observation. This currently means that the embryos are regularly removed from optimal incubation conditions to enable selection. This impacts their development capacity and prevents them from being monitored in real time.

ADVANTAGES

ATLIS(TM) is a new imaging system that uses an automated time lapse microscope and image processing to monitor embryos by taking regular images of them without removing them from their optimal development conditions.

The data is more precise, of higher quality and data analysis is sharper and simpler. With this instrument to aid in selection, the biologist can determine which embryo has the best implantation potential.

The system also makes it possible to monitor the embryos of several patients simultaneously.

APPLICATIONS

The ATLIS(TM) system is intended for medically assisted reproduction laboratories. It is a robotic platform that can be integrated to incubators already available on the market. A version of the device with an integrated incubator is also being developed.