Become a strategic partner for the industrialisation and commercialisation
of this innovation through an operating licence.

GYRO

Gene therapy for retinal dystrophies

Investment: 100k€

Scope: Health

Scientific field(s): Biology and Medicinal Chemistry

Institution(s): Université Paris-Saclay - CNRS

Development: Technology to be marketed

#Neuroprotection #GeneTherapy #RetinalDegeneration

#1

Agnostic gene therapy for all retinal degenerative diseases

#2

Long-lasting neuroprotective effect demonstrated in preclinical trials

#3

Mature technology with high scientific credibility

USE CASES

  • Agnostic product that can be applied to all retinal degenerative diseases.
  • The first applications are photoreceptor degenerative diseases, Age-related macular diseases (AMD), Glaucoma.

APPLICATIONS

  • A retinal neuroprotective protein has been discovered by the project team, based on their years of research on the underlying mechanism of action
  • A gene therapy product can efficiently induce a long-term neuroprotective effect

ADVANTAGES

  • Efficient neuroprotection
  • Long-term therapeutic effect with AAVs
  • Wide applications in retinal degenerative diseases
  • Safety in the therapeutic area
  • Expertise of the team in the domain